Regenerative Medicine

Platelet-Rich-Plasma-PRP-Therapy-in-New-York-Dr.-Jack-Bertolino-e1446750303775Veterinary Neurology and Pain Management Center of New England is excited to offer Regenerative Medicine Therapy! Regenerative medicine is the field that works to restore structure and function of damaged tissues and organs. Stem Cell Therapy utilizes the body’s own cells to regenerate and heal injured tissue, decrease inflammation, stimulate new blood supply, activate resident stem cells, stimulate healing and tissue growth, protect cells from death, and break down scar tissue in chronic conditions. Our bodies are made up of stem cells that are able to self-renew and differentiate themselves into other cell types. Stem cells act as our internal doctors and aid in healing our bodies from injuries and illnesses automatically. This therapy consists of different components and includes Platelet Rich Plasma (PRP), Bone Marrow Aspirate Concentrate (BMAC) Stem Cell therapy, and Adipose Stem Cell Therapy. Stem cells used for regenerative medicine are harvested from the patient’s bone marrow, adipose tissue, or from their own blood and can differentiate into cartilage, bone, tendons, and ligaments, muscle, nerves and other tissues for repair.

What is Platelet Rich Plasma?

Platelet Rich Plasma (PRP) is a highly concentrated blood sample that contains isolated cells (platelets) and the fluid portion of blood (plasma). When used as therapy, PRP can help regenerate and heal tissues by recruiting cells to an area of injury to clean up dead and injured cells, and by releasing proteins called Growth Factors which are responsible for tissue generation.

A small amount of blood is taken from your pet and is processed using a specialized system that concentrates the platelets and the plasma. Once the PRP processing is complete, it is injected directly into the area of injury.

What is Bone Marrow Aspirate Concentrate?

Stem cells have the ability to differentiate into any type of cell. They can also activate other surrounding stem cells and recruit additional cell types to aid in wound healing and tissue repair. Bone Marrow Stem Cells are a great option for many patients!

A small amount of bone marrow is collected from the one of the bones while your pet is under general anesthesia. It is then processed using a specialized system that isolates and concentrates the stem cells. Once the processing is complete, the stem cells are then directly injected into the area of injury.

As with PRP therapy, every dog’s response to therapy will be different.

What is Adipose Stem Cell Therapy?

Adipose Stem Cell Therapy is a form of Stem Cell Therapy that utilizes stem cells from adipose (fat) tissue and are a great source for regenerative mesenchymal cells and platelet growth factors for patients of all ages. Adipose tissue is a rich, and minimally invasive source of a high volume of stem cells that is safe and easy to harvest.

What is Amniotic Cell Therapy?

Recent studies have shown that while amniotic cells do not contain stem cells, they do share the same functions and healing properties.

What types of conditions can be treated using stem cell therapy?

  • Osteoarthritis
  • Acute and Chronic Soft Tissue Injuries
  • Muscle Injuries
  • Tendon injuries
  • Ligament injuries
  • Neurologic Conditions


If you are interested in learning more, please schedule an appointment to discuss whether your pet is a candidate for Stem Cell Therapy!

It is important to keep in mind that Regenerative Medicine is still a new form of therapy that is being studied in both human and veterinary medicine. It is not a 100% guarantee, but merely another option to possibly avoid surgery.

For more information regarding Regenerative Medicine and Stem Cell Therapy please look to the following peer-reviewed articles:

Regenerative Medicine For Soft Tissue Injury & Osteoarthritis (Today’s Veterinary Practice / NAVC, July/August 2016)

Partial cranial cruciate ligament Tears Treated with stem cell and Platelet-rich Plasma combination Therapy in 36 Dogs: A Retrospective Study (Frontiers in Veterinary Medicine, December 2016)


Pet’s Name: Molly

molly whalen

Our 10 year old Yorkshire terrier mix, Molly, tore her CCL and surgery wasn’t an option so we thought we’d never see our little dog run and romp again.  Luckily, our veterinarian was familiar with the work of Dr. Kube and recommended we bring Molly to Veterinary Neurology and Pain Management Center of New England.  There Molly received the latest in stem cell therapy and rehabilitation therapy including Hyperbaric Oxygen therapy, underwater treadmill, laser therapy, passive range of motion and massage.  Thanks to the competent, caring and friendly staff of technologists (Renee, Melissa, Chastity, Tricia, Lisa, and Jessica) and lots of hard work on Molly‘s part too, she is now  running and romping again!  On a recent walk along the beach, Molly walked right into the water and started walking around, which she had never done before.  We think she has fond memories of the underwater treadmill!  Thank you Dr. Kube and staff for letting Molly feel and act like a puppy again!!  We are so grateful!

Pet’s Name: Tito


titoAfter receiving stem cell treatment at Veterinary Neurology and Pain Management Center of New England Tito, our 11 year old Shepherd mix, has been doing amazing! So thankful that we don’t have to put him through a lengthy surgery at his age. We also attribute his recovery to the wonderful group of rehabilitation specialists there, they are all fantastic and he absolutely LOVES going. We were a little hesitant it wasn’t going to work, needless to say we were ecstatic when he was doing more and more at home and at rehab. No more limping and his muscle mass has returned. A huge thank you to Dr. Kube and her outstanding staff, too many names to mention but they are all the most loving, hard working, committed group and we trust them whole heartedly in any aspect of our boys well being.